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POSTDOCTORAL ASSOCIATE

Duke Health
Durham

Job Description

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nations top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Occ Summary

Conduct independent research activities under the guidance of a faculty mentor in preparation for afull-time academic or research career. Work Performed Seeking a highly motivated postdoctoral research associate to investigate genetic and epigenetic causes of late-onset Alzheimers disease. The successful applicant will have a strong and productive scientific record, be highly collaborative, inquisitive, diligent, and have previous experience in one or more of the relevant fields: human genetics, neurobiology, functional genomics, molecular biology, RNA biology, and bioinformatics.

The ideal candidate should be less than two years out from their Ph.D. and should demonstrate excellent verbal and written communication skills. The lab investigates genetic and molecular mechanisms controlling neurodegeneration and neuronal aging and contributing to neurodegenerative pathologies, and age-related brain diseases. To tackle these questions, we employ genomic technologies, single-cell analyses of human brain tissues, iPSC-derived models, humanized mouse, bioinformatics tools, and genomic/epigenomic/transcriptomic datasets. The lab has ongoing collaborations with labs at Duke as well as with other national and international investigators. The primary goal for this position will be to investigate the underpinnings of how Alzheimers GWAS discoveries translate to disease causal mechanisms. The postdoctoral associate will implement cutting-edge technologies in functional genomics, molecular profiling, single-cell analyses, and model systems primarily iPSC gene-edited derived neurons. Additionally, the postdoctoral associate will have the opportunity to pursue complementary projects in the lab at the intersection of molecular genetics and neurodegenerative diseases in aging.

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideasan exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

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